Pentapeptide-18
Functions / Benefits
Quality Specifications
| Specification Item | Standard |
|---|---|
| Grade | Cosmetic Grade |
| Recommended Usage | 0.001%–0.01% (w/w) in finished formulation |
| Property 1 | ≥98% HPLC |
| Property 2 | White powder |
| Property 3 | Water soluble |
Description
Pentapeptide-18, known as Leuphasyl, is an enkephalin-like neuropeptide that provides a gentle, cumulative approach to reducing expression lines. It works by mimicking the body's natural enkephalins to inhibit neuronal exocytosis, decreasing muscle contraction frequency and intensity beneath wrinkle-prone skin.
Leuphasyl's mechanism is more subtle than direct nAChR blockers like Syn-Ake, making it ideal for consumers who want wrinkle reduction without the sensation of muscle immobilization. It pairs excellently with other neuropeptides: combining Leuphasyl with Syn-Ake produces synergistic wrinkle reduction while maintaining natural appearance.
Clinical data shows progressive wrinkle depth reduction over 28 days of continuous use. Water-soluble, easy to formulate, and stable across a broad pH range. Recommended concentration: 1-4% in finished products.
COSPEP supplies high-purity Pentapeptide-18 (>98%) with full documentation including HPLC certificate, MS identification, and technical formulation support for commercial product development.