sh-Oligopeptide-2
Functions / Benefits
Quality Specifications
| Specification Item | Standard |
|---|---|
| Grade | Cosmetic Grade |
| Recommended Usage | 0.1–10 ppm (1–10 μg/g) in finished formulation |
| Property 1 | ≥95% SDS-PAGE |
| Property 2 | White lyophilized powder |
| Property 3 | ≥1×10⁵ IU/mg |
Description
sh-Oligopeptide-2 is the INCI designation for recombinant human Epidermal Growth Factor (EGF), one of the most potent cell-signaling molecules in skin biology. EGF binds to EGFR receptors on keratinocytes, fibroblasts, and endothelial cells, triggering cascades that promote cell proliferation, migration, and survival.
As a 53-amino acid polypeptide, sh-Oligopeptide-2 stimulates epithelial regeneration, accelerates wound closure, and enhances extracellular matrix production. Particularly valuable in post-procedure skincare, anti-aging formulations, and products targeting compromised skin barriers.
The recombinant production method ensures high purity, batch consistency, and freedom from animal-derived contaminants. Clinical applications demonstrate accelerated wound healing (up to 38% faster closure), improved skin texture, and reduced fine lines. Effective at 1-10 ppm.
COSPEP supplies recombinant sh-Oligopeptide-2 with comprehensive characterization including SDS-PAGE purity analysis, bioactivity assay, and endotoxin testing. Cold-chain shipping available for temperature-sensitive orders.